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Christina Applegate Gives Update After Multiple Sclerosis Misdiagnoses: ‘I’ll Never Leave This Community’

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CitrixNews Staff
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Christina Applegate Gives Update After Multiple Sclerosis Misdiagnoses: ‘I’ll Never Leave This Community’

By Charisma Madarang

Charisma Madarang

Contact Charisma Madarang on X Contact Charisma Madarang by Email View all posts by Charisma Madarang November 3, 2026 Add us as a Google Preferred Source US actress Christina Applegate (L) arrives for the 29th Screen Actors Guild Awards at the Fairmont Century Plaza in Century City, California, on February 26, 2023. (Photo by VALERIE MACON / AFP) (Photo by VALERIE MACON/AFP via Getty Images) VALERIE MACON/AFP via Getty Images

Christina Applegate shared an update following the news that she had been misdiagnosed with multiple sclerosis, five years after doctors told her she had the autoimmune disorder.

When speaking on the latest episode of MeSsy, her MS-themed podcast she hosts with Jamie Lynn Sigler, Applegate said that doctors are reevaluating the root of her symptoms.

“We’re going into square one, just doing some testing and going one by one of kind of the sister diseases to MS,” Applegate told guest Jack Osbourne, who has MS. “You’ve got RA [rheumatoid arthritis], and you’ve got lupus and Lyme disease and all these things that kind of can mimic MS,” Applegate said when discussing the medical testing she’s undergoing. “So, now I’m being tested for all that stuff, slowly but surely.”

The actress joked, “Talk about being a fraud. I don’t even have it anymore. Geez,” before emphasizing her dedication to the MS community: “I’ll never leave this community. We made so many lifelong friends, and I care so deeply about everybody that we represent and I represent. I’m still always going to be a part of it in one way or another.”

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