NFL Week 5 opens when the Dallas Cowboys host the Tampa Bay Buccaneers on Thursday Night Football. Dallas is favored by 9.5 points, according to the latest Week 5 NFL odds. Other notable Week 5 NFL spreads include Eagles vs. Jaguars (-6.5) in London, Bears vs. Packers (+3), 49ers vs. Seahawks (-3) and Bills vs. Rams (-2.5). Bet on every Week 5 NFL game with the latest DraftKings promo code, where new users get $150 in bonus bets after making a $5 wager:
Below you'll find the NFL betting odds for every Week 5 matchup. You can find the SportsLine Projection Model's NFL betting advice for Week 5 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get $55 as a sign-up bonus:
** Odds provided by DraftKings are subject to change **
Thursday, Oct. 8
Dallas Cowboys vs. Tampa Bay Buccaneers
Spread: Cowboys -9.5 Moneyline: Cowboys (-476), Buccaneers (+380) Total: 47.5
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Sunday, Oct. 11
Jacksonville Jaguars vs. Philadelphia Eagles
Spread: Jaguars -6.5 Moneyline: Jaguars (-275), Eagles (+240) Total: 42.5
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Green Bay Packers vs. Chicago Bears
Spread: Bears -3 Moneyline: Packers (+136), Bears (-142) Total: 45.5
Tennessee Titans vs. Houston Texans
Spread: Texans -7 Moneyline: Titans (+275), Texans (-323) Total: 39.5
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Miami Dolphins vs. Cincinnati Bengals
Spread: Bengals -7.5 Moneyline: Dolphins (+310), Bengals (-345) Total: 42.5
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New England Patriots vs. Las Vegas Raiders
Spread: Patriots -3.5 Moneyline: Patriots (-192), Raiders (+176) Total: 45.5
New Orleans Saints vs. Minnesota Vikings
Spread: Vikings -1.5 Moneyline: Saints (+102), Vikings (-118) Total: 42.5
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New York Jets vs. Cleveland Browns
Spread: Jets -2.5 Moneyline: Jets (-128), Browns (+110) Total: 39.5
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Pittsburgh Steelers vs. Indianapolis Colts
Spread: Steelers -2.5 Moneyline: Steelers (-135), Colts (+116) Total: 44.5
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Washington Commanders vs. New York Giants
Spread: Commanders -3 Moneyline: Commanders (-166), Giants (+154) Total: 43.5
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Los Angeles Chargers vs. Denver Broncos
Spread: Broncos -3.5 Moneyline: Chargers (+156), Broncos (-185) Total: 42.5
Arizona Cardinals vs. Detroit Lions
Spread: Lions -4.5 Moneyline: Cardinals (+198), Lions (-225) Total: 54.5
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Seattle Seahawks vs. San Francisco 49ers
Spread: Seahawks -3 Moneyline: Seahawks (-148), 49ers (+138) Total: 47
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Atlanta Falcons vs. Baltimore Ravens
Spread: Falcons -2.5 Moneyline: Falcons (-155), Ravens (+130) Total: 44
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Monday, Oct. 12
Los Angeles Rams vs. Buffalo Bills
Spread: Rams -2.5 Moneyline: Rams (-152), Bills (+135) Total: 54.5
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