The fourth-ranked UCLA Bruins will look to stay perfect on the season when they battle the visiting Illinois Fighting Illini in a key Big Ten matchup on Friday night. Illinois is coming off a 24-13 win over Nebraska on Nov. 6, while UCLA downed Minnesota 34-20 on Saturday to jump four spots in the latest College Football Playoff ranking. The Fighting Illini (6-3, 4-2 Big Ten), who are tied for third in the conference, are 2-1 on the road this season. The Bruins (9-0, 6-0 Big Ten), who lead the Big Ten, are 5-0 on their home field in 2026. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55:
Kickoff is set for 9 p.m. ET at the Rose Bowl in Pasadena, Calif. The Bruins are 10.5-point favorites, with the over/under at 48.5 in the latest Illinois vs. UCLA odds. Before making any Illinois vs. UCLA picks, check out the Illinois vs. UCLA predictions from the SportsLine Projection Model.
Illinois vs. UCLA odds
Illinois vs. UCLA spread
UCLA -10.5
Illinois vs. UCLA over/under
48.5 points
Illinois vs. UCLA money line
UCLA -391, Illinois +320
Illinois vs. UCLA picks
Illinois vs. UCLA streaming
Fubo (Try for free)Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after depositing $10:
Top Illinois vs. UCLA predictions
After simulating Illinois vs. UCLA 10,000 times, SportsLine model is going Over 48.5 points at betting apps and the best college football betting sites. The Over has hit in five of the last nine Illinois games, and in the last UCLA matchup. The Bruins enter as the third-highest scoring offense in the conference at 33.6 points per game. Illinois is 10th, averaging 28.4 points.
The model projects that Illinois quarterback Katin Houser will throw for more than 220 yards and one touchdown. He has thrown for 1,955 yards and 16 touchdowns with five interceptions on the season. UCLA quarterback Ty Dieffenbach, meanwhile, is projected to throw for over 230 yards and two scores. He has thrown for 986 yards and six touchdowns with two interceptions in 2026.
The computer is calling for 49 combined points as the Over is the value side 54% of the time. See the model's spread and money-line picks at SportsLine.
How to make Illinois vs. UCLA picks
In addition to going Over on the total, the model also says one side of the spread hits in well over 50% of simulations. You can only get the pick at SportsLine.
So who wins Illinois vs. UCLA, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that simulates each game 10,000 times, and find out.
