Well, that was fast. The Boys series finale only wrapped two days ago, but Prime Video clearly wants to build on that momentum by releasing the first teaser for the prequel series, Vought Rising. With spinoff series Gen V canceled after two seasons, Vought Rising and a planned The Boys: Mexico must carry the franchise banner.
(Spoilers for The Boys series finale below.)
The Boys' fifth season set up the final confrontation between Antony Starr’s Homelander and Karl Urban’s Butcher—the former seeking the original V compound that would make him immortal, the latter seeking to commit genocide with a Supe-specific virus. Homelander succeeded in his quest, but he wasn't quite an invulnerable god. There were heavy losses on both sides of the conflict (RIP Frenchie, in particular), and Homelander was ultimately defeated and killed by a vengeful Butcher. (Starr still hasn't gotten his much-deserved Emmy; his portrayal was simply magnificent.)