SportsLine's model reveals its Detroit Pistons vs. Minnesota Timberwolves predictions and NBA picks today
By Ross Kelly Apr 2, 2026 at 10:21 am ET • 2 min read 
Imagn Images A cross-conference matchup on Thursday's NBA schedule features the Detroit Pistons hosting the Minnesota Timberwolves. Detroit (55-21) is the No. 1 seed in the East and is coming off a Tuesday win over Toronto, 127-116. Minnesota (46-29) is the West's fifth seed and is coming off a 30-point Monday victory over Dallas. These teams just played on Saturday in which the Pistons prevailed 109-87. Anthony Edwards (knee) is listed as questionable for the Wolves.
Tip-off from is at 7 p.m. ET from Little Caesars Arena in Detroit. The Wolves lead the all-time series by the narrowest of margins with a 36-35 record. The latest Timberwolves vs. Pistons odds from DraftKings Sportsbook have Detroit as the 3.5-point favorite. The over/under for total points scored is 224.5. Before making any Pistons vs. Timberwolves picks, check out the Timberwolves vs. Pistons predictions from the SportsLine Projection Model.
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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered Week 24 on a sizzling 46-20 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.
Now, the model has simulated Timberwolves vs. Pistons 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model's picks. Here are several NBA odds and NBA betting lines for Pistons vs. Timberwolves:
Timberwolves vs. Pistons spread:
Detroit -3.5 at DraftKings
Timberwolves vs. Pistons over/under:
224.5 points
Timberwolves vs. Pistons money line:
Pistons -160, Timberwolves +134
Timberwolves vs. Pistons picks:
Timberwolves vs. Pistons streaming:
Prime Video
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Top Pistons vs. Timberwolves predictions
After 10,000 simulations of Timberwolves vs. Pistons, SportsLine's model is going Over on the total (224.5). Detroit has heavily leaned over as of late, as its games have eclipsed the total in back-to-back outings, as well as in four of the last five. For Minnesota, being on the road has had its contests lean over. The Wolves have seen the Over go 21-15 in away games, while Minnesota as a road underdog has the seen the Over hit 58.3% of the time.
Minnesota is projected to have the game's top two scorers, with Edwards going for more than 26 points. However, Detroit counters with superior balance in the absence of Cade Cunningham (lung). The Pistons are forecasted to have eight players score more than 8 points, compared to Minnesota's six players with more than 8 points. Both squads are projected to allow at least 4 more points than their season averages as the Over hits 59.9% of the time. See the Pistons vs. Timberwolves spread pick at SportsLine.
How to make Timberwolves vs. Pistons picks
After simulating each possession 10,000 times, the model also says one side of the spread hits well over 50% of the time. You can head to SportsLine to see the model's NBA picks.
So who wins Pistons vs. Wolves, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Wolves vs. Pistons line to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.
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